Light snow is possible Saturday night into Christmas Eve for a large part of the mid-section of the U.S. A broad shortwave trough will dig southeastward into Kansas and then move eastward into the Ohio Valley. This shortwave will generate strong vertical motion, which will aid in the development of snow from Kansas eastward into West Virginia. On the southern side of this shortwave, it is possible a few flurries may occur as far south as northern Oklahoma, northern Arkansas, and northern Tennessee.
Locations closer to the shortwave have the best chance to see accumulating snowfall. This region, near the Ohio Valley, will see the strongest lift and modeled soundings show the entire column will be below freezing. More importantly, the dendritic growth zone in the modeled soundings is near saturated. This is favorable for snow accumulation enhancement in which 1-3″ is likely. I would not be surprised to see 2-4″ in parts of central/northern Indiana and Ohio.